abstract：BACKGROUND:Intussusception (IS) is a form of acute intestinal obstruction that occurs mainly in infants and is usually of unknown cause. An association between IS and the first licensed rotavirus vaccine, a reassortant-tetravalent, rhesus-based rotavirus vaccine (RRV-TV), led to the withdrawal of the vaccine. New rotav...

journal_title：BMC gastroenterology

authors： Sáez-Llorens X,Velázquez FR,Lopez P,Espinoza F,Linhares AC,Abate H,Nuñez E,Venegas G,Vergara R,Jimenez AL,Rivera M,Aranza C,Richardson V,Macias-Parra M,Palacios GR,Rivera L,Ortega-Barria E,Cervantes Y,Rüttimann R,Ru

更新日期：2013-05-27 00:00:00

abstract：BACKGROUND:Measurements of CFTR function in rectal biopsies ex vivo have been used for diagnosis and prognosis of Cystic Fibrosis (CF) disease. Here, we aimed to evaluate this procedure regarding: i) viability of the rectal specimens obtained by biopsy forceps for ex vivo bioelectrical and biochemical laboratory analys...

journal_title：BMC gastroenterology

authors： Servidoni MF,Sousa M,Vinagre AM,Cardoso SR,Ribeiro MA,Meirelles LR,de Carvalho RB,Kunzelmann K,Ribeiro AF,Ribeiro JD,Amaral MD

更新日期：2013-05-20 00:00:00

abstract：BACKGROUND:Compared with biofluids, target tissues and organs more directly reflect the pathophysiological state of a disease process. In this study, a D-galactosamine (GalN) / lipopolysaccharide (LPS)-induced mouse model was constructed to investigate metabonomics of liver tissue and directly characterize metabolic ch...

journal_title：BMC gastroenterology

authors： Feng B,Wu S,Liu F,Gao Y,Dong F,Wei L

更新日期：2013-04-29 00:00:00

abstract：BACKGROUND:Chronic diarrhea in adults is a common symptom with a wide range of underlying etiologies. Although various strategies have been proposed for evaluation, there are still cases with undetermined origins even after extensive workup. Amyloidosis with gastrointestinal (GI) involvement is one of the causes that s...

journal_title：BMC gastroenterology

authors： Wang C,Li Y,Jin Y,Zhou W,Zhu Y,Yao F,Qian J

更新日期：2013-04-24 00:00:00

abstract：BACKGROUND:Intestinal ischemia-reperfusion injury (IRI) can occur in clinical scenarios such as organ transplantation, trauma and cardio-pulmonary bypass, as well as in neonatal necrotizing enterocolitis or persistent ductus arteriosus. Pharmacological protection by pretreating ("preconditioning") with opioids attenuat...

journal_title：BMC gastroenterology

authors： Cho SS,Rudloff I,Berger PJ,Irwin MG,Nold MF,Cheng W,Nold-Petry CA

更新日期：2013-04-22 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is common, with surgery as the main curative treatment. The prevalence of chronic liver disease has increased, but knowledge is limited on postoperative mortality in patients with liver disease who undergo CRC surgery. Hence, we examined 30-day mortality after CRC surgery in patients ...

journal_title：BMC gastroenterology

authors： Montomoli J,Erichsen R,Christiansen CF,Ulrichsen SP,Pedersen L,Nilsson T,Sørensen HT

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or colonic mucosa. It is suggested that the commensal bacteria of the digestive tract may play a ro...

journal_title：BMC gastroenterology

authors： Pilarczyk-Zurek M,Chmielarczyk A,Gosiewski T,Tomusiak A,Adamski P,Zwolinska-Wcislo M,Mach T,Heczko PB,Strus M

更新日期：2013-04-08 00:00:00

abstract：BACKGROUND:Inadequate response to proton pump inhibitor (PPI) therapy in patients with gastroesophageal reflux disease (GERD) is reported in up to 40%. Patients with non erosive reflux disease (NERD) have lower response rates compared to patients with erosive reflux disease (ERD); pH metry contributes to GERD diagnosis...

journal_title：BMC gastroenterology

authors： Kandulski A,Peitz U,Mönkemüller K,Neumann H,Weigt J,Malfertheiner P

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Acute pancreatitis is the most common complication of diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). In spite of continuing research, no pharmacologic agent capable of effectively reducing the incidence of ERCP-induced pancreatitis has found its way into clinical practise. ...

journal_title：BMC gastroenterology

authors： Fluhr G,Mayerle J,Weber E,Aghdassi A,Simon P,Gress T,Seufferlein T,Mössner J,Stallmach A,Rösch T,Müller M,Siegmund B,Büchner-Steudel P,Zuber-Jerger I,Kantowski M,Hoffmeister A,Rosendahl J,Linhart T,Maul J,Czakó L,

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:A novel in vitro system was employed to investigate liver tissue respiration (mitochondrial O2 consumption) in mice treated with concanavalin A (Con A). This study aimed to investigate hepatocyte bioenergetics in this well-studied hepatitis model. METHODS:C57Bl/6 and C57Bl/6 IFN-γ-/- mice were injected intr...

journal_title：BMC gastroenterology

authors： Al-Shamsi M,Shahin A,Mensah-Brown EP,Souid AK

更新日期：2013-01-12 00:00:00

abstract：BACKGROUND:Green tea has shown the role of chemoprevention for cancer. Recently, several studies suggested that green tea intake may have effect on esophageal cancer risk, whereas the results were inconsistent. METHODS:We performed a meta-analysis of all English and Chinese language studies of green tea consumption an...

journal_title：BMC gastroenterology

authors： Zheng P,Zheng HM,Deng XM,Zhang YD

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:Rumination syndrome (RS) is a functional gastrointestinal disorder (FGD) increasingly recognized in children and adolescents. The epidemiology of this condition in school aged children is poorly understood. The main objective of this study was to assess the prevalence of rumination and other related associat...

journal_title：BMC gastroenterology

authors： Rajindrajith S,Devanarayana NM,Crispus Perera BJ

更新日期：2012-11-16 00:00:00

abstract：BACKGROUND:The impact of viral subtype on the rate of sustained virological response (SVR) to antiviral therapy in patients chronically infected with hepatitis C genotype 1 subtype 1a and 1b has not been extensively investigated. The aim of this study is to determine whether the HCV genotype 1 subtypes 1a and 1b respon...

journal_title：BMC gastroenterology

authors： Pellicelli AM,Romano M,Stroffolini T,Mazzoni E,Mecenate F,Monarca R,Picardi A,Bonaventura ME,Mastropietro C,Vignally P,Andreoli A,Marignani M,D'Ambrosio C,Miglioresi L,Nosotti L,Mitidieri O,Gentilucci UV,Puoti C,Barba

更新日期：2012-11-16 00:00:00

abstract：BACKGROUND:Pancreatic Stone Protein (PSP) is a protein naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that blood PSP levels rise in the presence of inflammation or infection. However, it is not known whether PSP is superior to other established blood tests...

journal_title：BMC gastroenterology

authors： Tschuor C,Raptis DA,Limani P,Bächler T,Oberkofler CE,Breitenstein S,Graf R

更新日期：2012-10-25 00:00:00

abstract：BACKGROUND:Sleep disturbances are increasingly recognized as a common problem for children and adolescents with chronic pain conditions, but little is known about the prevalence, type, and impact of sleep problems in pediatric functional gastrointestinal disorders (FGIDs). The objectives of the current study were two-f...

journal_title：BMC gastroenterology

authors： Schurman JV,Friesen CA,Dai H,Danda CE,Hyman PE,Cocjin JT

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:Currently there is no disease-specific outcome measure to assess the health-related quality of life (HRQOL) of pediatric patients with Eosinophilic Esophagitis (EoE). Therefore, the objective of this qualitative study was to further develop and finalize the items and support the content validity for the new ...

journal_title：BMC gastroenterology

authors： Franciosi JP,Hommel KA,Greenberg AB,DeBrosse CW,Greenler AJ,Abonia JP,Rothenberg ME,Varni JW

更新日期：2012-09-25 00:00:00

abstract：BACKGROUNDS:Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in Asians. However, data on prevalence and factors associated with NAFLD in Asians are lacking. The aim of this study is to investigate the prevalence of NAFLD in Shanghai employees to assess the relationship between N...

journal_title：BMC gastroenterology

authors： Hu X,Huang Y,Bao Z,Wang Y,Shi D,Liu F,Gao Z,Yu X

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:MCAD-deficiency is the most common inborn error of fatty acid oxidation now included in many newborn screening programms using MS/MS. During prolonged catabolic episodes, patients may suffer from metabolic decompensation with dysfunction of liver, skeletal- and heart muscle as well as brain. In anabolism, ne...

journal_title：BMC gastroenterology

authors： Das AM,Drache S,Janzen N,Franke A

更新日期：2012-08-30 00:00:00

abstract：BACKGROUND:Controversy exists regarding the role of PD1 and its ligand PD-L1 in chronic hepatitis B infection. In some studies, persistent HBV infection has been attributed to high levels of PD-1 and PD-L1 expression on HBV-specific T-cells and antigen-presenting cells (APCs) respectively. Other studies revealed that t...

journal_title：BMC gastroenterology

authors： Wenjin Z,Chuanhui P,Yunle W,Lateef SA,Shusen Z

更新日期：2012-08-16 00:00:00

abstract：BACKGROUND:Enteroaggregative Escherichia coli (EAEC) causes diarrhea, malnutrition and poor growth in children. Human breast milk decreases disease-causing bacteria by supplying nutrients and antimicrobial factors such as lysozyme. Goat milk with and without human lysozyme (HLZ) may improve the repair of intestinal bar...

journal_title：BMC gastroenterology

authors： Carvalho EB,Maga EA,Quetz JS,Lima IF,Magalhães HY,Rodrigues FA,Silva AV,Prata MM,Cavalcante PA,Havt A,Bertolini M,Bertolini LR,Lima AA

更新日期：2012-08-11 00:00:00

abstract：BACKGROUND:Previous research has shown variation in the effects of patient factors, including hepatic necroinflammatory activity, on liver stiffness measurement (LSM). This prospective study attempts to identify explanatory factors for LSM in patients with chronic hepatitis C (CHC) using acoustic radiation force impuls...

journal_title：BMC gastroenterology

authors： Chen SH,Li YF,Lai HC,Kao JT,Peng CY,Chuang PH,Su WP,Chiang IP

更新日期：2012-08-10 00:00:00

abstract：BACKGROUND:Glycoprotein 2 (GP2) was discovered as the major autoantigen of Crohn's disease (CD)-specific pancreatic autoantibodies (PAB). We investigated anti-GP2 IgA and IgG antibodies as novel serological parameters in CD and assessed their association with distinct disease phenotypes. METHODS:Anti-GP2 and anti-Sacc...

journal_title：BMC gastroenterology

authors： Bogdanos DP,Roggenbuck D,Reinhold D,Wex T,Pavlidis P,von Arnim U,Malfertheiner P,Forbes A,Conrad K,Laass MW

更新日期：2012-08-06 00:00:00

abstract：BACKGROUND:Little data exists on the factors associated with health care seeking behaviour for primary symptoms of colorectal cancer (CRC). This study aimed to identify individual, provider and psychosocial factors associated with (i) ever seeking medical advice and (ii) seeking early medical advice for primary symptom...

journal_title：BMC gastroenterology

authors： Courtney RJ,Paul CL,Sanson-Fisher RW,Macrae FA,Attia J,McEvoy M

更新日期：2012-08-03 00:00:00

abstract：BACKGROUND:A tenth of patients with involuntary weight loss (IWL) have gastrointestinal cancer. Ferritin is the first parameter to be modified during the process leading to iron deficiency anaemia, therefore it should be the most sensitive. The aim of this study was to assess the ability of ferritin to rule out gastroi...

journal_title：BMC gastroenterology

authors： Baicus C,Caraiola S,Rimbas M,Patrascu R,Baicus A,GSSPI.

更新日期：2012-07-09 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the most common cancer in Europe with a mortality rate of almost 50%. The prognosis of patients is largely determined by the clinical and pathological stage at the time of diagnosis. Population screening has been shown to reduce CRC-related mortality rate. Most screening programs w...

journal_title：BMC gastroenterology

authors： Stegeman I,de Wijkerslooth TR,Mallant-Hent RC,de Groot K,Stroobants AK,Fockens P,Mundt M,Bossuyt PM,Dekker E

更新日期：2012-06-19 00:00:00

abstract：BACKGROUND:High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy. Whether oral proton pump inhibitor can replace intravenous proton pump inhibitor in this setting is unknown. This study aims to compare the clinical efficacy of oral and in...

journal_title：BMC gastroenterology

authors： Yen HH,Yang CW,Su WW,Soon MS,Wu SS,Lin HJ

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:Wireless capsule pH-metry (WC) is better tolerated than standard nasal pH catheter (SC), but endoscopic placement is expensive. AIMS:to confirm that non-endoscopic peroral manometric placement of WC is as effective and better tolerated than SC and to perform a cost analysis of the available esophageal pH-me...

journal_title：BMC gastroenterology

authors： Andrews CN,Sadowski DC,Lazarescu A,Williams C,Neshev E,Storr M,Au F,Heitman SJ

更新日期：2012-05-31 00:00:00

abstract：BACKGROUND:Colon cancer is one of the most aggressive human malignancies, with a very poor prognosis. Although it has been suggested that different isoforms of the lymphoid enhancer factor (LEF-1) have opposing biological activities, the biological outcome of aberrant LEF-1 activation in colon cancer is still unclear. ...

journal_title：BMC gastroenterology

authors： Wang SH,Nan KJ,Wang YC,Wang WJ,Tian T

更新日期：2012-05-28 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) symptoms often overlap. In some IBS cases there are subtle inflammatory changes similar to the immune-mediated pathophysiology of IBD, and the risk of both increases after infectious gastroenteritis (IGE). METHODS:To evaluate the effect of ...

journal_title：BMC gastroenterology

authors： Porter CK,Cash BD,Pimentel M,Akinseye A,Riddle MS

更新日期：2012-05-28 00:00:00

abstract：BACKGROUND:Treatment effectiveness of Helicobacter pylori varies regionally and is decreasing worldwide, principally as a result of antibiotic resistant bacterium. Tetracycline is generally included in second line H. pylori eradication regimens. In Brazil, a high level of tetracycline resistance (TetR) is mainly associ...

journal_title：BMC gastroenterology

authors： Suzuki RB,Almeida CM,Sperança MA

更新日期：2012-05-17 00:00:00

abstract：BACKGROUND:The natural course and treatment strategies for asymptomatic or oligosymptomatic pancreatic necrosis are still poorly defined. The aim of this retrospective study was to establish criteria for the need of intervention in patients with pancreatic necrosis. METHODS:A total of 31 consecutive patients (18 male,...

journal_title：BMC gastroenterology

authors： Jürgensen C,Arlt A,Neser F,Fritscher-Ravens A,Stölzel U,Hampe J

更新日期：2012-05-14 00:00:00

abstract：BACKGROUND:Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Necrotic tissue releases high mobility group B1 (HMGB1), and HMGB1 contributes to liver injury. Even though blockade of HMGB1 does not protect against APAP-induced acute liver injury (ALI) at 9 h time point, the later time points are not stud...

journal_title：BMC gastroenterology

authors： Yang R,Zhang S,Cotoia A,Oksala N,Zhu S,Tenhunen J

更新日期：2012-05-08 00:00:00

abstract：BACKGROUND:Diminished bone mineral density (BMD) is of significant concern in pediatric inflammatory bowel disease (IBD). Exact etiology is debatable. The recognition of fibroblast growth factor 23 (FGF23), a phosphaturic hormone related to tumor necrosis factor alpha (TNF-α) makes it plausible to hypothesize its possi...

journal_title：BMC gastroenterology

authors： El-Hodhod MA,Hamdy AM,Abbas AA,Moftah SG,Ramadan AA

更新日期：2012-05-02 00:00:00

abstract：BACKGROUND:Many studies suggest that in chronic hepatitis B virus (HBV) infection regulate T (Treg) cells and interlukin-17-producing T help cells (Th17) are mutually antagonistic in the immune response. This study is aimed to reveal the cell differentiation environment and the significance of Treg and Th17 balance in ...

journal_title：BMC gastroenterology

authors： Xue-Song L,Cheng-Zhong L,Ying Z,Mo-Bin W

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) patients failing medical management require colectomy. This study compares risk estimates for predictors of postoperative complication derived from administrative data against that of chart review and evaluates the accuracy of administrative coding for this population. METHODS:Hospit...

journal_title：BMC gastroenterology

authors： Ma C,Crespin M,Proulx MC,DeSilva S,Hubbard J,Prusinkiewicz M,Nguyen GC,Panaccione R,Ghosh S,Myers RP,Quan H,Kaplan GG

更新日期：2012-04-27 00:00:00

abstract：BACKGROUND:It is believed that inflammatory bowel diseases (IBD) result from an imbalance in the intestinal immune response towards the luminal microbiome. Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and upon recognition it mediates cytokine responses and skewing of the adaptive im...

journal_title：BMC gastroenterology

authors： Heinsbroek SE,Oei A,Roelofs JJ,Dhawan S,te Velde A,Gordon S,de Jonge WJ

更新日期：2012-04-16 00:00:00

abstract：BACKGROUND:The aims of this study were to assess the prevalence of hepatitis C virus (HCV) infection in Japanese patients with oral lichen planus and identify the impact of amino acid (aa) substitutions in the HCV core region and IFN-sensitivity-determining region (ISDR) of nonstructural protein 5A (NS5A) associated wi...

journal_title：BMC gastroenterology

authors： Nagao Y,Sata M

更新日期：2012-04-10 00:00:00

abstract：BACKGROUND:The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms. The aim of our study was to comparatively investigate the inhibitory effect on gastric acid secretion of a single oral administration of omeprazole plus mosapri...

journal_title：BMC gastroenterology

authors： Iida H,Inamori M,Fujii T,Sekino Y,Endo H,Hosono K,Nonaka T,Koide T,Takahashi H,Yoneda M,Goto A,Abe Y,Kobayashi N,Kirikoshi H,Kubota K,Saito S,Gotoh E,Maeda S,Nakajima A

更新日期：2012-03-26 00:00:00

abstract：BACKGROUND:Gastroesophageal reflux (GER) is a disorder that is common by seen in childhood and may lead to severe complications. In this study, we ascertained the incidence of GER among the children who had typical and atypical complaints of GER and whether there was a difference between two groups comparing the findin...

journal_title：BMC gastroenterology

authors： Uzun H,Alagoz D,Okur M,Dikici B,Kocabay K,Senses DA,Ozkan A,Kaya M

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We investigated the role of Glial-derived neurotrophic factor (GDNF) in t...

journal_title：BMC gastroenterology

authors： Steinkamp M,Gundel H,Schulte N,Spaniol U,Pflueger C,Zizer E,von Boyen GB

更新日期：2012-01-17 00:00:00